Paulo Koeberle

Dr. Koeberle completed his Ph.D in neurosciences at McMaster University in 2001. He then studied under Dr. Mathias Bähr at the University of Göttingen Germany as a postdoctoral fellow. After his final postdoctoral studies under Dr. Lyanne Schlichter (Toronto Western Research Institute) he was hired as an Assistant Professor in the Division of Anatomy. Dr. Koeberle’s research is focused on the molecular mechanisms of neurodegeneration in the adult central nervous system. Specific focus is placed on traumatic brain injury and stroke (ischemia), through the use of injury models of the visual system. Dr. Koeberle currently teaches Neuroanatomy for the Department of Physical Therapy, is the course director for the Physician's Assistant Program and contributed in the undergraduate stream at the University of Toronto.

Recent Publications

1. Neurosurgical Modeling of Retinal Ischemia-Reperfusion Injury. Shabanzadeh AP, D'Onofrio PM, Monnier PP, Koeberle PD. J Stroke Cerebrovasc Dis. 2018 Apr;27(4):845-856.
2. Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS. Tassew NG, Charish J, Shabanzadeh AP, Luga V, Harada H, Farhani N, D'Onofrio P, Choi B, Ellabban A, Nickerson PEB, Wallace VA, Koeberle PD, Wrana JL, Monnier PP. Cell Rep. 2017 Jul 5;20(1):99-111. 
3. Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke. Shabanzadeh AP, D'Onofrio PM, Monnier PP, Koeberle PD. Cell Death Dis. 2015 Nov 5;6:e1967. 
4. Uncoupling Neogenin association with lipid rafts promotes neuronal survival and functional recovery after stroke.
   Shabanzadeh AP, Tassew NG, Szydlowska K, Tymianski M, Banerjee P, Vigouroux RJ, Eubanks JH, Huang L, Geraerts M, Koeberle PD, Mueller BK, Monnier PP. Cell Death Dis. 2015 May 7;6:e1744.
5. Modifying lipid rafts promotes regeneration and functional recovery.
   Tassew NG, Mothe AJ, Shabanzadeh AP, Banerjee P, Koeberle PD, Bremner R, Tator CH, Monnier PP.
   Cell Rep. 2014 Aug 21;8(4):1146-59.